S-Gboxin
S-Gboxin is a functional analog of the oxidative phosphorylation (OXPHOS) inhibitor Gboxin and has antitumor activity. S-Gboxin inhibits the growth of mouse and human glioblastoma with an IC50 of 470 nM. S-Gboxin has antitumor activity[1].
Product Specifications
CAS Number
[2101317-21-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/S-Gboxin.html
Purity
99.62
Solubility
DMSO : 93.33 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 67°C)
Smiles
CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(CN2C(C=CC=C3)=C3[N+](C)=C2C4=CC(C(F)(F)F)=CC=C4)=O.[I-]
Molecular Formula
C27H32F3IN2O2
Molecular Weight
600.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Shi Y, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567 (7748) :341-346.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Mouse proliferating cell nuclear antigen antibody, PCNA ELISA Kit
Mouse proliferating cell nuclear antigen antibody, PCNA ELISA Kit
Mouse proliferating cell nuclear antigen antibody, PCNA ELISA Kit
Mouse proliferating cell nuclear antigen antibody, PCNA ELISA Kit