Pomalidomide-PEG2-OH
Pomalidomide-PEG3-OH (compound 53a) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984) -based cereblon ligand and a 2-unit PEG linker[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pomalidomide-peg2-oh.html
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCO)=CC=C3)=O)=O
Molecular Formula
C17H19N3O6
Molecular Weight
361.35
References & Citations
[1]Zhang X, Thummuri D, Liu X, Hu W, Zhang P, Khan S, Yuan Y, Zhou D, Zheng G. Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15;192:112186.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W924949/Pomalidomide-PEG2-OH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W924949/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
CAS Number
[2143097-10-1]
Available Sizes
Curated Selection
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