Lurasidone (Hydrochloride)
Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride) ) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride) ) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 nM.
Product Specifications
CAS Number
367514-88-3
Product Name Alternative
SM-13496 (Hydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Lurasidone-Hydrochloride.html
Purity
99.86
Solubility
Smiles
O=C([C@H]([C@H]1CC[C@@H]2C1)[C@H]2C3=O)N3C[C@@H]4CCCC[C@H]4CN(CC5)CCN5C6=NSC7=CC=CC=C76.Cl
Molecular Formula
C28H37ClN4O2S
Molecular Weight
529.14
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT1 Receptor;5-HT7 Receptor; D2 Receptor; mLAG-3; MUC3
Citation 01
Available Sizes
Frequently Asked Questions
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