PROTAC SMARCA2/4-degrader-3
SMARCA2/4-degrader-3 (compound I-433) is a PROTAC SMARCA2/4-degrader based on VH032-NH2, with a degradation potency (DC50) [1].
Product Specifications
CAS Number
2568507-10-6
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-smarca2-4-degrader-3.html
Smiles
O=C([C@H]1N(C[C@H](O)C1)C([C@@H](NC(C2CC3(CC(C4=CC=C(CN5CCC(CC5)CN6N=CC(C7=C(N)N=NC(C8=C(O)C=CC=C8)=C7)=C6)C=C4)C3)C2)=O)C(C)(C)C)=O)NCC9=CC=C(C%10=C(C)N=CS%10)C=C9
Molecular Formula
C56H66N10O5S
Molecular Weight
991.25
References & Citations
[1]Nan J, et al. Smarca degraders and uses thereof, US20230072658A1, 2023-03-09
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
453331-01 50 mg
L-Isolecucine 7-Amido-4-methylcoumarin Trifluoroacetate Salt
Sign In for Pricing
View Details 453331-02 100 mg
L-Isolecucine 7-Amido-4-methylcoumarin Trifluoroacetate Salt
Sign In for Pricing
View Details 