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Sigma-LIGAND-1 (hydrochloride)

Product Specifications

UNSPSC Description

Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a Ki of 4000 nM at the dopamine D2 receptor[1].

Target Antigen

Sigma Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sigma-ligand-1-hydrochloride.html

Purity

99.13

Solubility

DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C1C(C)=C(C2=CC=CC=C2)OC3=CC=C(OCCCCCCN4CCC(O)CC4)C=C13.[H]Cl

Molecular Weight

472.02

References & Citations

[1]Erickson RH, et al. (Aminoalkoxy)chromones. Selective sigma receptor ligands. J Med Chem. 1992 May 1;35(9):1526-35.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-101626A/Sigma-LIGAND-1-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-101626A/Sigma-LIGAND-1-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

139652-86-1

Available Sizes

Curated Selection

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