Sigma-LIGAND-1 (hydrochloride)
Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a Ki of 4000 nM at the dopamine D2 receptor[1].
Product Specifications
CAS Number
[139652-86-1]
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sigma-ligand-1-hydrochloride.html
Purity
99.13
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(C)=C(C2=CC=CC=C2)OC3=CC=C(OCCCCCCN4CCC(O)CC4)C=C13.[H]Cl
Molecular Formula
C27H34ClNO4
Molecular Weight
472.02
References & Citations
[1]Erickson RH, et al. (Aminoalkoxy) chromones. Selective sigma receptor ligands. J Med Chem. 1992 May 1;35 (9) :1526-35.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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