Sigma-LIGAND-1 (hydrochloride)
Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a Ki of 4000 nM at the dopamine D2 receptor[1].
Product Specifications
CAS Number
[139652-86-1]
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sigma-ligand-1-hydrochloride.html
Purity
99.13
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(C)=C(C2=CC=CC=C2)OC3=CC=C(OCCCCCCN4CCC(O)CC4)C=C13.[H]Cl
Molecular Formula
C27H34ClNO4
Molecular Weight
472.02
References & Citations
[1]Erickson RH, et al. (Aminoalkoxy) chromones. Selective sigma receptor ligands. J Med Chem. 1992 May 1;35 (9) :1526-35.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Browse additional items from our catalog
THRAP5 (Mediator Complex Subunit 16, DRIP92, THRAP5, TRAP95) (HRP)
