Importazole
Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.
Product Specifications
CAS Number
[662163-81-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Importazole.html
Purity
99.99
Solubility
DMSO : ≥ 33 mg/mL
Smiles
CC(NC1=C2C=CC=CC2=NC(N3CCCC3)=N1)C4=CC=CC=C4
Molecular Formula
C20H22N4
Molecular Weight
318.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Soderholm JF, et al. Importazole, a small molecule inhibitor of the transport receptor importin-β. ACS Chem Biol. 2011 Jul 15;6 (7) :700-8.|[2]Yan WQ, et al. Effect of nuclear receptor inhibitor importazole on the proliferation and apoptosis of multiple myeloma cells. Zhonghua Xue Ye Xue Za Zhi. 2013 Apr;34 (4) :323-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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