Sodium zirconium cyclosilicate
Product Specifications
Product Name Alternative
OPC-14857 (Standard); DM-14857 (Standard),OPC-14857-d8; DM-14857-d18
UNSPSC Description
Sodium zirconium cyclosilicate is an orally administered, non-absorbed, novel, inorganic microporous zirconium silicate compound, is a highly selective cation exchanger that selectively removes excess K+ in vivo. Sodium zirconium cyclosilicate can be used in research of chronic kidney disease (CKD)[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sodium-zirconium-cyclosilicate.html
Purity
95.0
Solubility
DMSO : < 1 mg/mL (ultrasonic)
Smiles
O[Si]1(O[Si](O)(O[Si](O)(O)O1)O)O.[Na].[Zr].[Na]
Molecular Weight
371.50
References & Citations
[1]Stavros F, et, al. Characterization of structure and function of ZS-9, a K+ selective ion trap. PLoS One. 2014 Dec 22;9(12):e114686.|[2]Ash SR, et, al. A phase 2 study on the treatment of hyperkalemia in patients with chronic kidney disease suggests that the selective potassium trap, ZS-9, is safe and efficient. Kidney Int. 2015 Aug;88(2):404-11.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119572/Sodium-zirconium-cyclosilicate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119572/Sodium-zirconium-cyclosilicate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
17141-74-1
Available Sizes
Curated Selection
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