Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

GARP&Latent TGF Beta 1 Complex, Human (HEK293, His-Avi)

GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β) . The presence of GARP affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing rat-derived GARP&Latent TGF Beta 1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L, respectively.

Product Specifications

Product Name Alternative

GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi), Rat, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/garp-latent-tgf-beta-1-complex-protein-human-hek293-his-avi.html

Molecular Formula

293135&59086 (Gene_ID) D3ZVD5 (I18-N628) &P17246 (L30-R278) (Accession)

Molecular Weight

Approximately 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (Latent TGF beta 1), based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Zimmer N, et al. GARP as a Therapeutic Target for the Modulation of Regulatory T Cells in Cancer and Autoimmunity. Front Immunol. 2022 Jul 8;13:928450.|[2]Tran DQ, et al. GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A. 2009 Aug 11;106 (32) :13445-50.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Gfra1 Rat shRNA Lentiviral Particle (Locus ID 25454)
TL709568V 500 µL Each

Gfra1 Rat shRNA Lentiviral Particle (Locus ID 25454)

Sign In for Pricing
View Details
SKA2 (FITC)
576399-01 50 µg

SKA2 (FITC)

Sign In for Pricing
View Details
SKA2 (FITC)
576399-02 100 µg

SKA2 (FITC)

Sign In for Pricing
View Details
Lentiviral mouse Enam shRNA (UAS) - Lentiviral mouse Enam shRNA (UAS) (25)
GTR15298496 1 Vial

Lentiviral mouse Enam shRNA (UAS) - Lentiviral mouse Enam shRNA (UAS) (25)

Sign In for Pricing
View Details
2-Hydroxy-6-methylbenzoic acid methyl ester
FH67529-01 250 mg

2-Hydroxy-6-methylbenzoic acid methyl ester

Sign In for Pricing
View Details
2-Hydroxy-6-methylbenzoic acid methyl ester
FH67529-02 500 mg

2-Hydroxy-6-methylbenzoic acid methyl ester

Sign In for Pricing
View Details