Z26395438
Z26395438 (compound 1) is a potent Sirtuin-1 inhibitor, with an IC50 value of 1.6 μM[1].
Product Specifications
CAS Number
2803-63-6
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/z26395438.html
Purity
99.59
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC1=CC=C(C(NCCC2=CNC3=CC=CC=C23)=O)C=C1
Molecular Formula
C17H15FN2O
Molecular Weight
282.31
References & Citations
[1]Gryniukova A, et al. AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1. J Med Chem. 2023 Aug 10;66 (15) :10241-10251.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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