(RS) -AMPA
(RS) -AMPA ((±) -AMPA) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS) -AMPA does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
Product Specifications
CAS Number
77521-29-0
Product Name Alternative
(±) -AMPA
UNSPSC
12352005
Hazard Statement
H302+H312+H332, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rs-ampa.html
Purity
99.82
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C1C(CC(N)C(O)=O)=C(C)ON1
Molecular Formula
C7H10N2O4
Molecular Weight
186.17
Precautions
H302+H312+H332, H315, H319, H335
References & Citations
[1]Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36 (1) :59-62.|[2]Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249 (4976) :1580-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor
Available Sizes
Frequently Asked Questions
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