PD 173955 analog 1
Product Specifications
UNSPSC Description
PD 173955 analog 1 (Compound 26) is an analog of PD 173955 (HY-10395). PD 173955 analog 1 is an inhibitor for EGFR kinase, which exhibits antitumor and toxicological properties. PD 173955 analog 1 exhibits an in silico IC50 of 0.19 μM[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-173955-analog-1.html
Smiles
O=C(O)C1=CC=CC(NC2=NC=C(C=C(C3=C(Cl)C=CC=C3Cl)C(N4C)=O)C4=N2)=C1
Molecular Weight
441.27
References & Citations
[1]Bagchi M C, et al., In silico evaluation of 6-(2, 6-dichlorophenyl)-pyrido [2, 3-d] pyrimidin-7 (8 H)-one compounds: an insight into design of less toxic anticancer drugs[J]. Medicinal Chemistry Research, 2016, 25: 123-134.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-18298/PD-173955-analog-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18298/
Clinical Information
No Development Reported
CAS Number
185039-99-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
