Lavofloxacin (lactate)
Lavofloxacin lactate ((-) -ofloxacin lactate) is a class of broad-spectrum antimicrobials that can kill or inhibit a variety of bacteria. Lavofloxacin lactate binds to DNA rotase and topoisomerase IV, resulting in blocked DNA replication and repair, thus inhibiting bacterial growth. Lavofloxacin lactate can be used to study resistance mechanisms in bacteria, including studying resistance genes and mutations[1].
Product Specifications
CAS Number
[294662-18-3]
Product Name Alternative
(-) -Ofloxacin (lactate)
UNSPSC
12352005
Hazard Statement
H302-H317-H334-H361-H362
Target
Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lavofloxacin-lactate.html
Smiles
O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O.CC(O)C(O)=O
Molecular Formula
C21H26FN3O7
Molecular Weight
451.45
Precautions
P260-P263-P264-P270-P272-P280-P284-P302+P352-P304+P340-P405-P501
References & Citations
[1]Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones[J]. Microbiology and molecular biology reviews, 1997, 61 (3) : 377-392.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
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