Eupenicisirenin C
Eupenicisirenin C (compound 1) is a sirenin derivative. Eupenicisirenin C has strong NF-κB inhibitory activities. Eupenicisirenin C suppresses effects on cGAS-STING pathway. Eupenicisirenin C inhibits RANKL-induced osteoclast differentiation in bone marrow macrophage cells[1].
Product Specifications
CAS Number
[2968309-12-6]
UNSPSC
12352211
Target
NF-κB; STING
Type
Natural Products
Related Pathways
Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/eupenicisirenin-c.html
Solubility
10 mM in DMSO
Smiles
COC(CC[C@]1(C)[C@]2([H])[C@@]1([H])C=C(CC2)C(O)=O)=O
Molecular Formula
C13H18O4
Molecular Weight
238.28
References & Citations
[1]Jian Cai, et al. Discovery of a novel anti-osteoporotic agent from marine fungus-derived structurally diverse sirenins. Eur J Med Chem. 2023.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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