Cu (II) GTSM
Cu (II) GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. Cu (II) GTSM inhibits Amyloid-β oligomers (AβOs) and decreases tau phosphorylation. Cu (II) GTSM also decreases the abundance of Amyloid-β trimers. Cu (II) GTSM is a potential anticancer and antimicrobial agent[1][2].
Product Specifications
CAS Number
68341-14-0
UNSPSC
12352100
Target
Amyloid-β; GSK-3
Type
Reference compound
Related Pathways
Neuronal Signaling; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/cu-ii-gtsm.html
Purity
95.0
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCL; heat to 60°C)
Smiles
CNC1=N[N]2=CC=[N]3N=C(NC)[S-][Cu+2]23[S-]1
Molecular Formula
C6H10CuN6S2
Molecular Weight
293.86
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GSK-3β
Available Sizes
Frequently Asked Questions
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