(Rac)-Ruxolitinib-d9
Product Specifications
UNSPSC Description
(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9) is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor[1].
Target Antigen
Isotope-Labeled Compounds; JAK
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics;JAK/STAT Signaling;Others;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
N#CCC(C1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])N2C=C(C=N2)C3=C4C(NC=C4)=NC=N3
Molecular Weight
315.42
References & Citations
[1]Yaoyu CHEN, et al. Combination therapy comprising an alk2 inhibitor and a jak2 inhibitor. Patent WO2021102258A1|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
2469553-67-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
46411124 3 x 1.0μg DNA
Tcp10a CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details