BPH-652
BPH-652 is a S. aureus dehydrosqualene synthase (CrtM) inhibitor, with a Ki of 1.5 nM and an IC50 of 100-300 nM (S. aureus pigment formation) [1].
Product Specifications
CAS Number
157124-84-0
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bph-652.html
Purity
98.97
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
O=S(C(P(O[K])(O[K])=O)CCCC1=CC=CC(OC2=CC=CC=C2)=C1)(O[K])=O
Molecular Formula
C16H16K3O7PS
Molecular Weight
500.63
References & Citations
[1]Liu CI, et al. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 7;319 (5868) :1391-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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