Bortezomib-pinanediol
Bortezomib-pinanediol is a proteasome inhibitor and a prodrug of Bortezomib (HY-10227) . Bortezomib-pinanediol inhibits cell growth and can be used for study of multiple myeloma[1].
Product Specifications
CAS Number
[205393-22-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bortezomib-pinanediol.html
Concentration
10mM
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=NC=CN=C1)N[C@@H](CC2=CC=CC=C2)C(N[C@H](B3O[C@@]4([H])[C@@]([C@](C5)([H])C(C)(C)[C@]5([H])C4)(C)O3)CC(C)C)=O
Molecular Formula
C29H39BN4O4
Molecular Weight
518.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Gu Z, et al. Hyaluronic acid shell and disulfide-crosslinked core micelles for in vivo targeted delivery of bortezomib for the treatment of multiple myeloma. Acta Biomater. 2018;80:288-295.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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