HIV capsid modulator 2
HIV capsid modulator 2 (Compound 7t) is a modulator for the HIV capsid (CA) protein. HIV capsid modulator 2 exhibits antiviral activity, which inhibits HIV-1 IIIB strain and HIV-2 ROD strain with EC50 of 0.04 and 0.13 μM. HIV capsid modulator 2 is metabolically stable in human liver microsomes[1].
Product Specifications
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-capsid-modulator-2.html
Smiles
FC1=CC(F)=CC(C[C@H](NC(CC2=CNC3=C2C=C(NS(=O)(C)=O)C=C3)=O)C(N(C)C4=CC=C(OC)C=C4)=O)=C1
Molecular Formula
C28H28F2N4O5S
Molecular Weight
570.61
References & Citations
[1]Jiang X, et al., Discovery of low-molecular-weight phenylalanine derivatives as novel HIV capsid modulators with improved antiretroviral activity and metabolic stability. J Med Virol. 2024 Apr;96 (4) :e29594.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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