HIV capsid modulator 2

HIV capsid modulator 2 (Compound 7t) is a modulator for the HIV capsid (CA) protein. HIV capsid modulator 2 exhibits antiviral activity, which inhibits HIV-1 IIIB strain and HIV-2 ROD strain with EC50 of 0.04 and 0.13 μM. HIV capsid modulator 2 is metabolically stable in human liver microsomes[1].

Product Specifications

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hiv-capsid-modulator-2.html

Smiles

FC1=CC(F)=CC(C[C@H](NC(CC2=CNC3=C2C=C(NS(=O)(C)=O)C=C3)=O)C(N(C)C4=CC=C(OC)C=C4)=O)=C1

Molecular Formula

C28H28F2N4O5S

Molecular Weight

570.61

References & Citations

[1]Jiang X, et al., Discovery of low-molecular-weight phenylalanine derivatives as novel HIV capsid modulators with improved antiretroviral activity and metabolic stability. J Med Virol. 2024 Apr;96 (4) :e29594.