What is the catalog number for Recombinant Human CD40 ligand protein (CD40LG) (Active)?

The catalog number for Recombinant Human CD40 ligand protein (CD40LG) (Active) is AP73323.

What sizes are available for Recombinant Human CD40 ligand protein (CD40LG) (Active)?

Recombinant Human CD40 ligand protein (CD40LG) (Active) is available in the following size(s): Inquire.

Recombinant Human CD40 ligand protein (CD40LG) (Active)

Q: Is Recombinant Human CD40 ligand protein (CD40LG) (Active) in stock?

Recombinant Human CD40 ligand protein (CD40LG) (Active) is currently made to order / not held in immediate stock. Contact us for lead time.

Product Specifications

Background

Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. {ECO:0000269|PubMed:15193700}.; Release of soluble CD40L from platelets is partially regulated by GP IIb, IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway. {ECO:0000269|PubMed:15193700}.

Product Name Alternative

CD40-L, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD antigen CD154

Gene ID

959

UniProt

P29965

Target

MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL

Purification

>95% as determined by SDS-PAGE and HPLC.

Bioactivity

Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng, ml.

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.