5-Nitrobarbituric acid
5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor (IC50=1.7 μM) [1].
Product Specifications
CAS Number
[480-68-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5-nitrobarbituric-acid.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC(=O)C(C(=O)N1)[N+](=O)[O-]
Molecular Formula
C4H3N3O5
Molecular Weight
173.08
Precautions
H302, H315, H319, H335
References & Citations
[1]J V de Julián-Ortiz, et al. Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. J Med Chem. 1999 Aug 26;42 (17) :3308-14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSV-1
Available Sizes
Curated Selection
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