BiP inducer X
BiP inducer X, a selective inducer of immunoglobulin heavy chain binding protein (BiP) /GRP78, is an effective ER (endoplasmic reticulum) stress inhibitor. BiP inducer X preferentially induces BiP with slight inductions of GRP94, calreticulin, and C/EBP homologous protein. BiP inducer X protects neurons from ER stress[1][2].
Product Specifications
CAS Number
101714-41-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bip-inducer-x.html
Concentration
10mM
Purity
99.62
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
N#CSCC(C1=CC(O)=C(O)C=C1)=O
Molecular Formula
C9H7NO3S
Molecular Weight
209.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Kudo T, et al. A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ. 2008;15 (2) :364-375. |[2]Yoo SA, et al. A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis. J Exp Med. 2012;209 (4) :871-886.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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