BiP inducer X

BiP inducer X, a selective inducer of immunoglobulin heavy chain binding protein (BiP) /GRP78, is an effective ER (endoplasmic reticulum) stress inhibitor. BiP inducer X preferentially induces BiP with slight inductions of GRP94, calreticulin, and C/EBP homologous protein. BiP inducer X protects neurons from ER stress[1][2].

Product Specifications

CAS Number

[101714-41-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bip-inducer-x.html

Concentration

10mM

Purity

99.62

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

N#CSCC(C1=CC(O)=C(O)C=C1)=O

Molecular Formula

C9H7NO3S

Molecular Weight

209.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Kudo T, et al. A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ. 2008;15 (2) :364-375. |[2]Yoo SA, et al. A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis. J Exp Med. 2012;209 (4) :871-886.