KLA peptide
KLA peptide a cationic amphipathic mitochondrial membrane disrupting peptide that induces cell apoptosis by disrupting mitochondrial membrane. KLA peptide can be used for the researches of cancer, inflammation, and neurological disease[1][2].
Product Specifications
CAS Number
184240-26-4
UNSPSC
12352209
Target
Apoptosis
Type
Peptides
Related Pathways
Apoptosis
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kla-peptide.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N
Molecular Formula
C72H138N20O15
Molecular Weight
1523.99
References & Citations
[1]Guo Z, et al. Specific hepatic stellate cell-penetrating peptide targeted delivery of a KLA peptide reduces collagen accumulation by inducing apoptosis. J Drug Target. 2017 Sep;25 (8) :715-723.|[2]Zen R, et al. Pro-inflammatory microglia-targeted peptide therapy ameliorates neonatal hypoxic-ischemic encephalopathy in mice. Mol Ther. 2025 Jul 2;33 (7) :3177-3194.
Shipping Conditions
Blue Ice
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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