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C3a [Trp63, 64] peptide

C3a [Trp63, 64] peptide

Product Specifications

Source

Synthetic

Field of Research

Cell Biology

Purity

> 95%

Form

Lyophilized powder

Molecular Weight

1820.19

Storage Conditions

Shipped at 4°C. Store at -20°C for one year.

Notes

For research use only.

Applications Notes

[Trp63, 64]-C3a (63-77), synthetic superagonist analog of complement 3a, exhibited the greatest biological potency of all peptides tested. The peptide was 12-15 times more active than natural C3a. Such an optimal potency was obtained by introducing a bulky hydrophobic group such as Trp-Trp which binds more strongly to the hydrophobic site on the receptor than does the corresponding site on the natural ligand.

AA Sequence

Trp-Trp-Gly-Lys-Lys-Tyr-Arg-Ala-Ser-Lys-Leu-Gly-Leu-Ala-Arg

Available Sizes

Frequently Asked Questions

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