Ghrelin peptide

Product Specifications

Source

Synthetic

Field of Research

Metabolism Research

Purity

> 95%

Form

Lyophilized powder

Molecular Weight

651.73

Storage Conditions

Shipped at 4°C. Store at -20°C for one year.

Notes

For research use only.

Applications Notes

Growth hormone secretagogue (GSH) receptor agonist based on the primary structure of ghrelin (IC50 = 10 μM) . (Trp3, Arg5) -Ghrelin (1-5) (GSWFR) stimulated growth hormone secretion after intravenous or oral administration and centrally administered GSWFR increased food intake in non-fasted mice. The orexigenic effect could be inhibited by (D-Lys3) -GHRP-6 and also by the NPY Y1 receptor antagonist BIBO3304 suggesting that GSWFR-induced feeding is mediated by the NPY Y1 receptor.