Calcitriol-d6

Calcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR) [1][2][3].

Product Specifications

CAS Number

[78782-99-7]

UNSPSC

12352211

Hazard Statement

H225, H319

Target

Isotope-Labeled Compounds; VD/VDR

Type

Isotope-Labeled Compounds

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Purity

99.27

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C=C1/C(C[C@H](C[C@@H]1O)O)=C\C=C2CCC[C@]3(C)[C@@H]([C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)CC[C@@]/23[H]

Molecular Formula

C27H38D6O3

Molecular Weight

422.67

Precautions

H225, H319

References & Citations

[1]Canalejo, et al. The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004) |[2]Nijenhuis, et al. The novel vitamin D analog ZK191784 as an intestine-specific vitamin D antagonist. FASEB J. 2006 20 1589.|[3]Nair SN, et al. A liquid chromatography/electrospray ionization tandem mass spectrometric method for quantification of asiatic acid from plasma: application to pharmacokinetic study in rats. Rapid Commun Mass Spectrom. 2012 Sep 15;26 (17) :1899-908.