4-Hydroxynonenal alkyne

4-Hydroxynonenal alkyne (4-HNE alkyne) is a click chemical reagent containing alkynes. 4-Hydroxynonenal alkyne induces heme oxygenase and cell apoptosis in colon cancer (RKO) cells[1].

Product Specifications

CAS Number

[1011268-23-7]

Product Name Alternative

4-HNE alkyne

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-hydroxynonenal-alkyne.html

Concentration

6.57 mM * 100 μL in Methyl acetate

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C/C=C/C(O)CCCC#C

Molecular Formula

C9H12O2

Molecular Weight

152.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Vila A, et al. Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives. Chem Res Toxicol. 2008 Feb;21 (2) :432-44.