Orexin B Human peptide
Orexin B Human peptide
Product Specifications
Product Name Alternative
Hypocretin-2 (human)
Source
Synthetic
Purity
> 95%
Form
Lyophilized powder
Molecular Weight
2899.4
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Notes
For research use only.
Applications Notes
Like orexin A, orexin B is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of orexin B to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX1 receptor is significantly lower (IC50 = 240 nM) than that of orexin A. Binding affinities for the OX2 receptor are similar for orexin A and B (IC50 = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor) .
AA Sequence
Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Available Sizes
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