Dermaseptin I peptide
Dermaseptin I peptide
Product Specifications
Source
Synthetic
Purity
> 95%
Form
Lyophilized powder
Molecular Weight
3455.08
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Notes
For research use only.
Applications Notes
Dermaseptin was originally isolated from skin extracts of the South American arboreal frog, Phyllomedusa sauvagei. The strongly basic, nonhemolytic compound is the first vertebrate peptide that shows highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. With a potentially amphiphatic α-helix structure, dermaseptin probably acts by membrane permeabilization.
AA Sequence
Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Leu-Gly-Ala-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln
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