Amylin, Feline peptide
Amylin, Feline peptide
Product Specifications
Source
Synthetic
Purity
> 95%
Form
Lyophilized powder
Molecular Weight
3910.45
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Notes
For research use only.
Applications Notes
Endogenous peptide secreted by pancreatic β-cells. Potently activates amylin, calcitonin (EC50 = 0.67 nM), CGRP and adrenomedullin receptors. Highly potently inhibitor of insulin-stimulated glucose uptake in skeletal muscle cells (IC50 = 12 pM) . Implicated in type II diabetes.
AA Sequence
H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Ile-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Ala-Ile-Leu-Ser-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge Cys2-Cys7)
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