Encainide

Encainide (MJ9067) is an antiarrhythmic agent with class IC activity. Encainide blocks voltage-dependent potassium channels. Encainide has the potential for life-threatening ventricular arrhythmias, symptomatic ventricular arrhythmias and supraventricular arrhythmias research[1][2].

Product Specifications

CAS Number

[66778-36-7]

Product Name Alternative

MJ9067

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/encainide.html

Purity

99.92

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=CC=C1CCC2N(C)CCCC2)C3=CC=C(OC)C=C3

Molecular Formula

C22H28N2O2

Molecular Weight

352.47

Precautions

H315, H319, H335

References & Citations

[1]R N Brogden, et al. Encainide. A review of its pharmacological properties and therapeutic efficacy. Drugs. 1987 Nov;34 (5) :519-38.|[2]Hongliang Li, et al. Encainide, a class Ic anti-arrhythmic agent, blocks voltage-dependent potassium channels in coronary artery smooth muscle cells. Korean J Physiol Pharmacol. 2023 Jul 1;27 (4) :399-406.