Human MAOB / Monoamine Oxidase B Protein
Monoamine Oxidase Type B (MAOB) is an enzyme located in the outer mitochondrial membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the breakdown of dopamine in the brain. MAOB inhibitors, that reduces dopamine turnover, are in clinical use for the treatment of Parkinson's disease (PD) .
Product Specifications
Product Name Alternative
MAOB, MAO-B, Monoamine Oxidase B, Monoamine oxidase type B
UniProt
P27338
Expression Region
Ser 2 - Val 520
Reactivity
Human
Conjugation
Unconjugated
Tag
N-10xHis
Source
Human MAOB, His Tag (orb1184801) is expressed from Baculovirus-Insect cells. It contains AA Ser 2 - Val 520 (Accession # P27338-1) .
Field of Research
Metabolism Research
Endotoxin
1.0 EU per μg
Purity
90%
Form
Liquid
Molecular Weight
60.6 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 60.6 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) .
NCBI Accession Number
P27338
Preservative
50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Available Sizes
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