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Human Tau-441 / 2N4R Protein

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Product Specifications

Product Name Alternative

DDPAC, FTDP-17, MAPT, MSTD, MTBT1, Tau, PHF-tau, TAU

UniProt

P10636

Expression Region

Met 1 - Leu 441

Reactivity

Human

Conjugation

Unconjugated

Tag

Native

Source

Human Tau-441, Tag Free (orb1184792) is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8) .

Field of Research

Neuroscience

Endotoxin

0.01 EU per μg

Purity

90%

Form

Liquid

Molecular Weight

45.8 kDa

Storage Conditions

-70°C

Notes

For research use only.

Applications Notes

This protein carries no "tag". The protein has a calculated MW of 45.8 kDa. The protein migrates as 30-53 kDa and 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

NCBI Accession Number

P10636

Preservative

50 mM Tris, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, pH7.5

Available Sizes

Frequently Asked Questions

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