Human Tau-441 / 2N4R Protein
Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
Product Specifications
Product Name Alternative
DDPAC, FTDP-17, MAPT, MSTD, MTBT1, Tau, PHF-tau, TAU
UniProt
P10636
Expression Region
Met 1 - Leu 441
Reactivity
Human
Conjugation
Unconjugated
Tag
Native
Source
Human Tau-441, Tag Free (orb1184792) is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8) .
Field of Research
Neuroscience
Endotoxin
0.01 EU per μg
Purity
90%
Form
Liquid
Molecular Weight
45.8 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
NCBI Accession Number
P10636
Preservative
50 mM Tris, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, pH7.5
Available Sizes
Frequently Asked Questions
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