What is the catalog number for Human Cathepsin S / CTSS Protein?

The catalog number for Human Cathepsin S / CTSS Protein is orb1184780.

What sizes are available for Human Cathepsin S / CTSS Protein?

Human Cathepsin S / CTSS Protein is available in the following size(s): 50 µg, 1 mg.

How many pack sizes does Human Cathepsin S / CTSS Protein come in?

Human Cathepsin S / CTSS Protein is available in 2 different pack sizes.

Is Human Cathepsin S / CTSS Protein in stock?

Human Cathepsin S / CTSS Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Human Cathepsin S / CTSS Protein

Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.

Product Specifications

Product Name Alternative

CTSS, Cathepsin S

UniProt

P25774

Expression Region

Gln 17 - Ile 331

Reactivity

Human

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human Cathepsin S, His Tag (orb1184780) is expressed from human 293 cells (HEK293) . It contains AA Gln 17 - Ile 331 (Accession # P25774-1) .

Endotoxin

1.0 EU per μg

Purity

90%

Form

Liquid

Molecular Weight

37.7 kDa

Storage Conditions

-70°C

Notes

For research use only.

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.7 kDa. The protein migrates as 38-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. The protein was designed as the pro-form (AA 17-331) . However, due to the inherent autoprocessing nature of Cathepsin S, the activation peptide is partially cleaved during expression and purification. Consequently, the final product coexists as a mixture of the pro-form (AA 17-331) and the mature form (AA 115-331) .