7-epi-Isogarcinol
7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migration[1].
Product Specifications
CAS Number
1141378-40-6
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Natural Products
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7-epi-isogarcinol.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@]23C(OC(C)([C@H](C3)C/C=C(C)\C)C)=C(C([C@@]1(C(C)([C@H](C2)C/C=C(C)\C)C)C/C=C(C)\C)=O)C(C4=CC(O)=C(C=C4)O)=O
Molecular Formula
C38H50O6
Molecular Weight
602.80
References & Citations
[1]Xu ZH, et al. Polycyclic Polyprenylated Acylphloroglucinols Bearing a Lavandulyl-Derived Substituent from Garcinia xanthochymus Fruits. J Nat Prod. 2022 Dec 23;85 (12) :2845-2855.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
STAT3
Available Sizes
Frequently Asked Questions
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