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Human KIR2DL3 Protein, Fc Tag

Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7) . KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.

Product Specifications

UniProt

P43628

Expression Region

His 22 - His 245

Reactivity

Human

Conjugation

Unconjugated

Tag

C-Fc

Field of Research

Immunology & Inflammation

Endotoxin

1.0 EU per μg

Purity

95%

Form

Powder

Molecular Weight

51.0 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

P43628

Preservative

50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Available Sizes

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