(4S) -4-Hydroxy-D-proline methyl ester (hydrochloride)
(4S) -4-Hydroxy-D-proline methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . (4S) -4-Hydroxy-D-proline methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Product Specifications
CAS Number
[481704-21-6]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tans-4-hydroxy-d-proline-methyl-ester-hydrochloride.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(OC)[C@@H]1NC[C@H](C1)O.Cl
Molecular Formula
C6H12ClNO3
Molecular Weight
181.62
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
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