Psoralidin
Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR) -induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties[1]. Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation[2].
Product Specifications
CAS Number
18642-23-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; COX; Lipoxygenase; Notch; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Psoralidin.html
Purity
99.90
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C/C(C)=C\CC1=C(C=C2OC(C3=C(C2=C1)OC4=C3C=CC(O)=C4)=O)O
Molecular Formula
C20H16O5
Molecular Weight
336.34
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
5-LOX; COX-2
Available Sizes
Frequently Asked Questions
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