Trifloxystrobin

Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases[1][2][3][4][5].

Product Specifications

CAS Number

[141517-21-7]

Product Name Alternative

CGA 279202

UNSPSC

12352005

Hazard Statement

H317, H410

Target

Apoptosis; Caspase; Fungal; PARP

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Trifloxystrobin.html

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C/C(C1=CC(C(F)(F)F)=CC=C1)=N\OCC2=C(C=CC=C2)/C(C(OC)=O)=N\OC

Molecular Formula

C20H19F3N2O4

Molecular Weight

408.37

Precautions

H317, H410

References & Citations

[1]Jang Y, et al. Trifloxystrobin induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) -mediated apoptosis in HaCaT, human keratinocyte cells [J]. Drug and Chemical Toxicology, 2017, 40 (1) : 67-73.|[2]Nguyen K, et al. Neurotoxicity assessment of QoI strobilurin fungicides azoxystrobin and trifloxystrobin in human SH-SY5Y neuroblastoma cells: Insights from lipidomics and mitochondrial bioenergetics[J]. Neurotoxicology, 2022, 91: 290-304.|[3]Li H, et al. Developmental toxicity, oxidative stress and immunotoxicity induced by three strobilurins (pyraclostrobin, trifloxystrobin and picoxystrobin) in zebrafish embryos [J]. Chemosphere, 2018, 207: 781-790.|[4]Wu R, et al. Oxidative stress and DNA damage induced by trifloxystrobin on earthworms (Eisenia fetida) in two soils [J]. Science of The Total Environment, 2021, 797: 149004.|[5]Villares M, et al. Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance [J]. Communications Biology, 2022, 5 (1) : 1253.