BMT-046091
BMT-046091 is a selective inhibitor of adaptor-associated kinase 1 (AAK1) . BMT-046091 inhibits phosphorylation of the μ2 peptide by AAK1 with an IC50 value of 2.8 nM[1].
Product Specifications
CAS Number
[1551401-20-7]
UNSPSC
12352005
Target
AAK1
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bmt-046091.html
Smiles
O=C1NC2=CC(OC[C@@H](N)CC(C)C)=CC=C2C3=CC=NC=C13
Molecular Formula
C18H21N3O2
Molecular Weight
311.38
References & Citations
[1]Justin V Louis, et al. [3H]BMT-046091 a potent and selective radioligand to determine AAK1 distribution and target engagement. Neuropharmacology. 2017 May 15:118:167-174.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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