BMT-046091

BMT-046091 is a selective inhibitor of adaptor-associated kinase 1 (AAK1) . BMT-046091 inhibits phosphorylation of the μ2 peptide by AAK1 with an IC50 value of 2.8 nM[1].

Product Specifications

CAS Number

[1551401-20-7]

UNSPSC

12352005

Target

AAK1

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bmt-046091.html

Smiles

O=C1NC2=CC(OC[C@@H](N)CC(C)C)=CC=C2C3=CC=NC=C13

Molecular Formula

C18H21N3O2

Molecular Weight

311.38

References & Citations

[1]Justin V Louis, et al. [3H]BMT-046091 a potent and selective radioligand to determine AAK1 distribution and target engagement. Neuropharmacology. 2017 May 15:118:167-174.