Mal-PEG2-Val-Cit-PABA-PNP
Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1345681-52-8]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg2-val-cit-paba-pnp.html
Purity
96.82
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(OC1=CC=C(C=C1)[N+]([O-])=O)OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCN3C(C=CC3=O)=O)=O)=O)=O
Molecular Formula
C34H41N7O13
Molecular Weight
755.73
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Available Sizes
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