Endothelin-3 Human peptide
Endothelin-3 Human peptide
Product Specifications
Product Name Alternative
ET-3 (human, mouse, rabbit, rat)
Source
Synthetic
Purity
> 95%
Form
Lyophilized powder
Molecular Weight
2643.1
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Notes
For research use only.
Applications Notes
ET-1, ET-2, and ET-3 are the products of three distinct endothelin genes. ET-2 and ET-3 are similar to ET-1, but differ in two and six amino acids, respectively. All three isopeptides produce strong in vitro vasoconstrictor and in vivo pressor responses. However, the quantitative profiles of their pharmacological activities vary greatly.
AA Sequence
H-Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bridge Cys1-Cys15, Cys3-Cys11)
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