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OT-551 (free base)

OT-551 (free base) is a lipophilic, disubstituted hydroxylamine with antioxidant properties. OT-551 can be used as an eye drop and can be converted by intraocular esterases to its active metabolite, Tempol-H (TP-H) . OT-551 can be utilized in geographic atrophy and macular degeneration research[1].

Product Specifications

CAS Number

[627085-11-4]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ot-551-free-base.html

Smiles

O=C(C1CC1)OC2CC(C)(N(O)C(C)(C)C2)C

Molecular Formula

C13H23NO3

Molecular Weight

241.33

References & Citations

[1]Wong WT, et al. Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial. Invest Ophthalmol Vis Sci. 2010 Dec;51 (12) :6131-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Curated Selection

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