E3 ligase Ligand 32
Product Specifications
UNSPSC Description
E3 ligase Ligand 32 (First product in Example 52) is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 32 can be connected to the ligand for protein by a linker to form PROTACs and can be used for the synthesis of PROTAC SMARCA2/4-degrader-29 (HY-162743)[1].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-32.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1NC(=O)C(CC1)N2C3=C(C=C(Br)C=C3)N(C)C2=O
Molecular Weight
338.161
References & Citations
[1]Nan Ji, et al. Smarca degraders and uses thereof. Worldwide applications 2020 US WO
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W382038/E3-ligase-Ligand-32-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W382038/E3-ligase-Ligand-32-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2300099-98-1
Available Sizes
Curated Selection
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