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Cytarabine triphosphate (trisodium)

Cytarabine triphosphate (Ara-CTP) trisodiu, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine[1].

Product Specifications

CAS Number

[1179343-17-9]

Product Name Alternative

Ara-CTP (trisodium)

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cytarabine-triphosphate-trisodium.html

Concentration

100 mM * 500 μL in Water

Purity

96.78

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@@](N2C(N=C(C=C2)N)=O)([H])O[C@@H]([C@H]1O)COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O

Molecular Formula

C9H13N3Na3O14P3

Molecular Weight

549.10

References & Citations

[1]Anderson E, et, al. Intracellular cytarabine triphosphate in circulating blasts post-treatment predicts remission status in patients with acute myeloid leukemia. Exp Hematol. 2019 Jun;74:13-18.e3.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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