MYX1715
MYX1715 is an inhibitor of N-Myristoyltransferase (NMT) with a KD value of 0.09 nM. MYX1715 inhibits the proliferation of LU0884 and LU2511 with IC50 values of 44 nM and 9 nM. MYX1715 exhibits antitumor efficacy against neuroblastoma and gastric cancer in mouse models. MYX1715 can be used as ADC toxin[1][2].
Product Specifications
CAS Number
2445448-66-6
UNSPSC
12352005
Target
ADC Payload; N-myristoyltransferase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/myx1715.html
Concentration
10mM
Purity
99.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N(C)C)C1=NN(C)C(C)=C1CCOC2=C(C3=CN4C(CCN)=CN=C4C=C3)C=CC(Cl)=C2
Molecular Formula
C25H29ClN6O2
Molecular Weight
480.99
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL
Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker) (KRT16/1714), CF594 conjugate, 0.1mg/mL
NKX2.8 (NKX28/3233R), CF640R conjugate, 0.1mg/mL
