BAZ1A-IN-1
BAZ1A-IN-1 is a potent inhibitor of BAZ1A (bromodomain-containing protein) . BAZ1A-IN-1 shows a KD value of 0.52 μM against BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-viability activity against cancer cell lines expressing a high level of BAZ1A, but weak or no activity against cancer cells with a low expression level of BAZ1A[1].
Product Specifications
CAS Number
[941521-45-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/baz1a-in-1.html
Purity
99.91
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=CC([N+]([O-])=O)=C1)NC2=NC(C3=CC=CC=C3)=CS2
Molecular Formula
C16H12N4O3S
Molecular Weight
340.36
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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